The feline allergen (Fel-d1) element is known to be produced by most cats according to researchers. Hundreds of adult Siberians were used in a study conducted by members of the Siberian Research. The data was collected in November 2009 from adult breeding Siberians. The study was conducted in Virginia based Biotechnologies laboratory.
Saliva samples were collected from each cat. They were tested and compared against other samples collected along with a bitter agent. Special actions were completed to ensure accuracy of information collected. The study had two elements that showed consistency including Sulfa and Metranitazole (Flagil). The rate of error varied depending on the cat with 40 percent in kittens under 9 months and 20 percent in adult cats. More advanced testing methods for breeds are available at KittenTesting.com.
The study discarded results using Citric Acid and Drontal to induce saliva. Previous studies have should Citric Acid has a tendency to affect results by changing flow rates of proteins and enzymes found in saliva. The ingredient was considered inapproriate for Fel d-1 allergen levels. Roughly 50 percent of Siberians had lower levels of Fel-d1 that average cats.
The study showed under 15 percent of Siberians could be in homes with dangerous or severe reactions to cats due to low allergen levels. More offspring was produced with low allergen mattings and lower levels of Fel-d1. Individual cats that were tested individually had between 0.1 mcg or about 16 mcg. When the tests were conducted multiple times their results varied.